Our research aims to study the Effect of Set in the process of perception of unconscious information. In the experiments, we use serial (multiple) unconscious stimulation and the modified masked priming technique to give unconscious stimuli to our participants. In the experiments we demonstrate that, as a result of the specially organized preliminary experimental series, it is possible to receive the steady priming-effect for the unconscious stimulus which initially didn’t render any noticeable influence on the effectiveness of the tasks solutions. We can conclude, that at unconscious level cognitive system analyzes series of unconscious influences. So, the nature of influence of each following unconscious stimulus on the current conscious cognitive activity, by the time of its occurrence, is already set on the basis of the analysis of the previous series of influences. It is possible to model these individual settings in the experimental environment.